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Numb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination.
Zhou, Liang; Yang, Dong; Wang, De-Juan; Xie, Ya-Jun; Zhou, Jia-Huan; Zhou, Lin; Huang, Hao; Han, Shuo; Shao, Chong-Yu; Li, Hua-Shun; Zhu, J Julius; Qiu, Meng-Sheng; De Zeeuw, Chris I; Shen, Ying.
Afiliação
  • Zhou L; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Yang D; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Wang DJ; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Xie YJ; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Zhou JH; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Zhou L; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Huang H; Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Hangzhou 310029, China;
  • Han S; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Shao CY; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China;
  • Li HS; SARITEX Center for Stem Cell Engineering Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200123, China;
  • Zhu JJ; Department of Pharmacology, School of Medicine, University of Virginia, Charlottesville, VA 22908;
  • Qiu MS; Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Hangzhou 310029, China;
  • De Zeeuw CI; Department of Neuroscience, Erasmus University Medical Center, 3000 CA, Rotterdam, The Netherlands; Netherlands Institute for Neuroscience, Royal Dutch Academy for Arts and Sciences, Meibergdreef 47, Amsterdam, The Netherlands yshen@zju.edu.cn c.dezeeuw@erasmusmc.nl.
  • Shen Y; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang University School of Medicine, Hangzhou 310058, China; yshen@zju.edu.cn c.dezeeuw@erasmusmc.nl.
Proc Natl Acad Sci U S A ; 112(50): 15474-9, 2015 Dec 15.
Article em En | MEDLINE | ID: mdl-26621723
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células de Purkinje / Sinapses / Cerebelo / Receptores de Glutamato Metabotrópico / Proteínas de Membrana / Atividade Motora / Proteínas do Tecido Nervoso Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células de Purkinje / Sinapses / Cerebelo / Receptores de Glutamato Metabotrópico / Proteínas de Membrana / Atividade Motora / Proteínas do Tecido Nervoso Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article