MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis.

Kindrat, Iryna; Tryndyak, Volodymyr; de Conti, Aline; Shpyleva, Svitlana; Mudalige, Thilak K; Kobets, Tetyana; Erstenyuk, Anna M; Beland, Frederick A; Pogribny, Igor P

Kindrat, Iryna; Tryndyak, Volodymyr; de Conti, Aline; Shpyleva, Svitlana; Mudalige, Thilak K; Kobets, Tetyana; Erstenyuk, Anna M; Beland, Frederick A; Pogribny, Igor P.

Afiliação

Kindrat I; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA.
Tryndyak V; Department of Biological and Medical Chemistry, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.
de Conti A; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA.
Shpyleva S; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA.
Mudalige TK; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA.
Kobets T; Office of Regulatory Affairs, Arkansas Regional Laboratory, U.S. Food and Drug Administration, Jefferson, AR, USA.
Erstenyuk AM; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA.
Beland FA; Department of Biological and Medical Chemistry, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.
Pogribny IP; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA.

Oncotarget ; 7(2): 1276-87, 2016 Jan 12.

Article em En | MEDLINE | ID: mdl-26657500

Assuntos

Antígenos CD/genética; Carcinoma Hepatocelular/genética; Regulação Neoplásica da Expressão Gênica; Neoplasias Hepáticas/genética; MicroRNAs/genética; Receptores da Transferrina/genética; 2-Acetilaminofluoreno/toxicidade; Animais; Antígenos CD/metabolismo; Western Blotting; Carcinogênese/efeitos dos fármacos; Carcinogênese/genética; Carcinógenos/toxicidade; Carcinoma Hepatocelular/metabolismo; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; Células Hep G2; Humanos; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/patologia; Neoplasias Hepáticas Experimentais/induzido quimicamente; Neoplasias Hepáticas Experimentais/genética; Neoplasias Hepáticas Experimentais/metabolismo; Masculino; Ratos Sprague-Dawley; Receptores da Transferrina/metabolismo; Reação em Cadeia da Polimerase Via Transcriptase Reversa

Palavras-chave

dysregulation; hepatocellular carcinoma; iron metabolism; microRNA-152; transferrin receptor 1

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores da Transferrina / Antígenos CD / Regulação Neoplásica da Expressão Gênica / Carcinoma Hepatocelular / MicroRNAs / Neoplasias Hepáticas Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google