Your browser doesn't support javascript.
loading
A population-based study investigating chronic rhinosinusitis and the incidence of asthma.
Habib, Al-Rahim R; Javer, Amin R; Buxton, Jane A.
Afiliação
  • Habib AR; St. Paul's Sinus Centre, Division of Otolaryngology, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada.
  • Javer AR; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Buxton JA; St. Paul's Sinus Centre, Division of Otolaryngology, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada.
Laryngoscope ; 126(6): 1296-302, 2016 06.
Article em En | MEDLINE | ID: mdl-26692188
ABSTRACT
OBJECTIVES/

HYPOTHESIS:

Chronic rhinosinusitis (CRS) is an inflammatory disease of the paranasal sinuses, associated with reduced health-related quality of life and increased utilization of healthcare services. Chronic upper and lower respiratory diseases often coexist, although the extent to which CRS is associated with developing asthma remains unclear. To investigate the effect of CRS on receiving a subsequent diagnosis of asthma, we used data from a previously conducted national, longitudinal survey.

METHODS:

Respondents from the Canadian National Population Health Survey from 1998/1999 to 2010/2011 were used. Data were analyzed from 11,555 (66.9%) subjects, ≥ 19 years of age and reporting no asthma at baseline. Respondents were reviewed for 12 years to determine the cumulative incidence of asthma. Logistic regression was used to estimate the effect of CRS on the development of asthma, adjusting for age, gender, body mass index, cigarette smoking, and food- or nonfood-related allergies.

RESULTS:

During the 12-year study period, 6.0% (95% confidence interval [CI] [95% CI] 5.4%-6.7%) of respondents developed asthma. Baseline CRS (odds ratio [OR] 2.7, 95% CI 1.9-3.9), female gender (OR 1.4, 95% CI 1.1-1.8), and allergies (OR 2.6, 95% CI 2.1 - 3.3) were significantly associated with developing asthma. After adjustment, respondents with CRS were significantly more likely to develop asthma than non-CRS counterparts (OR 2.0, 95% CI 1.4-2.9).

CONCLUSION:

Results indicate that one in 13 individuals with CRS will be subsequently diagnosed with asthma. Given the economic burden and use of healthcare services associated with asthma, providers managing CRS may consider increased awareness and subsequent treatment for asthma. LEVEL OF EVIDENCE 4. Laryngoscope, 1261296-1302, 2016.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Sinusite / Rinite Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Sinusite / Rinite Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Ano de publicação: 2016 Tipo de documento: Article