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The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation.
Rutten, Julie W; Klever, Roselin R; Hegeman, Ingrid M; Poole, Dana S; Dauwerse, Hans G; Broos, Ludo A M; Breukel, Cor; Aartsma-Rus, Annemieke M; Verbeek, J Sjef; van der Weerd, Louise; van Duinen, Sjoerd G; van den Maagdenberg, Arn M J M; Lesnik Oberstein, Saskia A J.
Afiliação
  • Rutten JW; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. j.w.rutten@lumc.nl.
  • Klever RR; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. r.r.klever@lumc.nl.
  • Hegeman IM; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. i.m.hegeman@lumc.nl.
  • Poole DS; Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands. d.poole@lumc.nl.
  • Dauwerse HG; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. j.g.dauwerse@lumc.nl.
  • Broos LA; Department of Clinical Genetics, K5-R, Leiden University Medical Center, PO Box 9600, 2300, RC, Leiden, The Netherlands. j.g.dauwerse@lumc.nl.
  • Breukel C; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. l.a.m.broos@lumc.nl.
  • Aartsma-Rus AM; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. c.breukel@lumc.nl.
  • Verbeek JS; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. a.m.aartsma-rus@lumc.nl.
  • van der Weerd L; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. j.s.verbeek@lumc.nl.
  • van Duinen SG; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. L.van_der_Weerd@lumc.nl.
  • van den Maagdenberg AM; Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands. L.van_der_Weerd@lumc.nl.
  • Lesnik Oberstein SA; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. S.G.van_Duinen@lumc.nl.
Acta Neuropathol Commun ; 3: 89, 2015 Dec 29.
Article em En | MEDLINE | ID: mdl-26715087
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Regulação da Expressão Gênica / CADASIL / Receptores Notch / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Regulação da Expressão Gênica / CADASIL / Receptores Notch / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article