Pituitary apoplexy: considerations on a single center experience and review of the literature.
J Endocrinol Invest
; 39(7): 739-46, 2016 Jul.
Article
em En
| MEDLINE
| ID: mdl-26733212
ABSTRACT
PURPOSE:
To present a single-center experience on pituitary tumor apoplexy and a review of literature focusing on predisposing and precipitating factors.METHODS:
Clinical presentation of our series of cases. Contemporary published literature is also reviewed.RESULTS:
The definition of this syndrome has not been consistent although now the majority of authors agree to definite it as an acute condition caused by hemorrhage or infarction of a pre-existing pituitary adenoma. Different predisposing and precipitating factors have been described in literature; among these antithrombotic and anticoagulant drugs, seem to play relevant roles. The clinical cases observed in our clinic confirm these data and suggest a probable association between elderly patients taking anticoagulant therapy and pituitary apoplexy adenoma.CONCLUSION:
Pituitary tumor apoplexy remains a challenging disease in relation to difficulties in correct diagnosis and thus in appropriate treatment. Antithrombotic/anticoagulant therapy may have an important role as precipitating factor. When a pituitary disorder is known, great care should be taken in the prescription of anticoagulant therapy.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Apoplexia Hipofisária
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article