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Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human ß2 Adrenoceptor.
Rosethorne, Elizabeth M; Bradley, Michelle E; Gherbi, Karolina; Sykes, David A; Sattikar, Afrah; Wright, John D; Renard, Emilie; Trifilieff, Alex; Fairhurst, Robin A; Charlton, Steven J.
Afiliação
  • Rosethorne EM; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Bradley ME; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Gherbi K; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Sykes DA; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Sattikar A; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Wright JD; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Renard E; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Trifilieff A; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Fairhurst RA; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
  • Charlton SJ; Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., M.E.B., K.G., D.A.S., A.S., J.D.W., S.J.C.); Novartis Institutes for Biomedical Research, Basel, Switzerland (E.R., A.T., R.A.F.); and School of Life Sciences, Queen's Medical Centre, University of Nottingham,
Mol Pharmacol ; 89(4): 467-75, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26772612
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Adrenérgicos beta 2 / Agonistas de Receptores Adrenérgicos beta 2 Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Adrenérgicos beta 2 / Agonistas de Receptores Adrenérgicos beta 2 Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article