Self-Exfoliated Guanidinium-Based Ionic Covalent Organic Nanosheets (iCONs).
J Am Chem Soc
; 138(8): 2823-8, 2016 Mar 02.
Article
em En
| MEDLINE
| ID: mdl-26866697
ABSTRACT
Covalent organic nanosheets (CONs) have emerged as functional two-dimensional materials for versatile applications. Although π-π stacking between layers, hydrolytic instability, possible restacking prevents their exfoliation on to few thin layered CONs from crystalline porous polymers. We anticipated rational designing of a structure by intrinsic ionic linker could be the solution to produce self-exfoliated CONs without external stimuli. In an attempt to address this issue, we have synthesized three self-exfoliated guanidinium halide based ionic covalent organic nanosheets (iCONs) with antimicrobial property. Self-exfoliation phenomenon has been supported by molecular dynamics (MD) simulation as well. Intrinsic ionic guanidinium unit plays the pivotal role for both self-exfoliation and antibacterial property against both Gram-positive and Gram-negative bacteria. Using such iCONs, we have devised a mixed matrix membrane which could be useful for antimicrobial coatings with plausible medical benefits.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Guanidina
/
Nanoestruturas
/
Anti-Infecciosos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article