Relative biological effectiveness (RBE) of p(26) + Be neutrons from the King Faisal Specialist Hospital and Research Centre CS-30 cyclotron measured by testis weight loss.
Strahlenther Onkol
; 165(11): 817-23, 1989 Nov.
Article
em En
| MEDLINE
| ID: mdl-2688155
ABSTRACT
Testis weight loss of C3H and Swiss-Webster (SW) mice was used as endpoint to determine the relative biological effectiveness (RBE) of p(26) + Be fast neutrons with respect to Co-60 gamma irradiation. Percent weight loss versus dose curves showed two components. Comparing first component effects, the RBE was 3.4 (C3H) and 3.7 (SW); when the second component was used, the RBE was 2.6 and 2.7 (C3H), and 3.5 (SW). When percent weight loss was plotted versus log dose, parallel lines were obtained, giving an RBE of 3.9 and 4.1 (C3H), and 4.2 (SW). Results were compared with published values and RBE as a function of fast neutron energy was plotted. A good correlation was found. Discrepancies seem to be mostly due to the use of different baseline radiation. When a constant correction is made, most of the values fit a single line. The possibility of using this approach as a substitute for international comparisons is discussed.
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Base de dados:
MEDLINE
Assunto principal:
Aceleradores de Partículas
/
Teleterapia por Radioisótopo
/
Testículo
/
Radioisótopos de Cobalto
/
Nêutrons Rápidos
/
Nêutrons
Limite:
Animals
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article