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A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
Schmidt, Florian I; Lu, Alvin; Chen, Jeff W; Ruan, Jianbin; Tang, Catherine; Wu, Hao; Ploegh, Hidde L.
Afiliação
  • Schmidt FI; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.
  • Lu A; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115 Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
  • Chen JW; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.
  • Ruan J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115 Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
  • Tang C; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115 Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
  • Wu H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115 Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115 wu@crystal.harvard.edu ploegh@wi.mit.edu.
  • Ploegh HL; Whitehead Institute for Biomedical Research, Cambridge, MA 02142 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 wu@crystal.harvard.edu ploegh@wi.mit.edu.
J Exp Med ; 213(5): 771-90, 2016 05 02.
Article em En | MEDLINE | ID: mdl-27069117
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Proteínas do Citoesqueleto / Anticorpos de Cadeia Única / Inflamassomos Limite: Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Proteínas do Citoesqueleto / Anticorpos de Cadeia Única / Inflamassomos Limite: Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article