Discordance of Mutation Statuses of Epidermal Growth Factor Receptor and K-ras between Primary Adenocarcinoma of Lung and Brain Metastasis.

Rau, Kun-Ming; Chen, Han-Ku; Shiu, Li-Yen; Chao, Tsai-Ling; Lo, Yi-Ping; Wang, Chin-Chou; Lin, Meng-Chih; Huang, Chao-Cheng

Rau, Kun-Ming; Chen, Han-Ku; Shiu, Li-Yen; Chao, Tsai-Ling; Lo, Yi-Ping; Wang, Chin-Chou; Lin, Meng-Chih; Huang, Chao-Cheng.

Afiliação

Rau KM; Division of Hematology-Oncology, Department of Internal Medicine, Kaohsiung 833, Taiwan. kmrau58@adm.cgmh.org.tw.
Chen HK; Chang Gung Memorial Hospital, Kaohsiung, Taiwan and Chang Gung University College of Medicine, Tao-Yuan 333, Taiwan. kmrau58@adm.cgmh.org.tw.
Shiu LY; Department of Pathology, Yuan's General Hospital, Kaohsiung 802, Taiwan. chenhanku@gmail.com.
Chao TL; Biobank and Tissue Bank, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan. her2neu24@gmail.com.
Lo YP; Department of Medical Research, Cell Therapy and Research Center, E-Da Hospital, I-shou University, Kaohsiung 840, Taiwan. her2neu24@gmail.com.
Wang CC; Department of Laboratory Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan. tsaeling@cgmh.org.tw.
Lin MC; Biobank and Tissue Bank, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan. monica0977@hotmail.com.
Huang CC; Chang Gung Memorial Hospital, Kaohsiung, Taiwan and Chang Gung University College of Medicine, Tao-Yuan 333, Taiwan. ccwang52@adm.cgmh.org.tw.

Int J Mol Sci ; 17(4): 524, 2016 Apr 07.

Article em En | MEDLINE | ID: mdl-27070580

Assuntos

Adenocarcinoma/genética; Adenocarcinoma/patologia; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/secundário; Receptores ErbB/genética; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Mutação; Proteínas Proto-Oncogênicas p21(ras)/genética; Adenocarcinoma de Pulmão; Idoso; Idoso de 80 Anos ou mais; Encéfalo/metabolismo; Encéfalo/patologia; Neoplasias Encefálicas/patologia; Feminino; Humanos; Pulmão/metabolismo; Pulmão/patologia; Masculino; Pessoa de Meia-Idade

Palavras-chave

EGFR mutation; K-ras mutation; adenocarcinoma of lung; brain metastasis; target therapy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Adenocarcinoma / Proteínas Proto-Oncogênicas p21(ras) / Receptores ErbB / Neoplasias Pulmonares / Mutação Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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