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Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 2.
McBride, Christopher; Cheruvallath, Zacharia; Komandla, Mallareddy; Tang, Mingnam; Farrell, Pamela; Lawson, J David; Vanderpool, Darin; Wu, Yiqin; Dougan, Douglas R; Plonowski, Artur; Holub, Corine; Larson, Chris.
Afiliação
  • McBride C; Medicinal Chemistry, Takeda California, United States.
  • Cheruvallath Z; Medicinal Chemistry, Takeda California, United States.
  • Komandla M; Medicinal Chemistry, Takeda California, United States.
  • Tang M; Medicinal Chemistry, Takeda California, United States.
  • Farrell P; Biological Sciences, Takeda California, United States.
  • Lawson JD; Computational Sciences, Takeda California, United States.
  • Vanderpool D; Biological Sciences, Takeda California, United States.
  • Wu Y; Biological Sciences, Takeda California, United States.
  • Dougan DR; Structural Biology, Takeda California, United States.
  • Plonowski A; Biological Sciences, Takeda California, United States.
  • Holub C; Biological Sciences, Takeda California, United States.
  • Larson C; Biological Sciences, Takeda California, United States.
Bioorg Med Chem Lett ; 26(12): 2779-2783, 2016 Jun 15.
Article em En | MEDLINE | ID: mdl-27136719
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Peso Corporal / Glicoproteínas / Inibidores Enzimáticos / Descoberta de Drogas / Aminopeptidases / Indóis / Obesidade Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Peso Corporal / Glicoproteínas / Inibidores Enzimáticos / Descoberta de Drogas / Aminopeptidases / Indóis / Obesidade Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article