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Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans.
Hohmann, Nicolas; Reinhard, Raphael; Schnaidt, Sven; Witt, Lukas; Carls, Alexandra; Burhenne, Jürgen; Mikus, Gerd; Haefeli, Walter E.
Afiliação
  • Hohmann N; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
  • Reinhard R; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
  • Schnaidt S; Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, Germany.
  • Witt L; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
  • Carls A; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
  • Burhenne J; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
  • Mikus G; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
  • Haefeli WE; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany walter.emil.haefeli@med.uni-heidelberg.de.
J Antimicrob Chemother ; 71(8): 2241-7, 2016 08.
Article em En | MEDLINE | ID: mdl-27141088
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasma / Midazolam / Fármacos Anti-HIV / Interações Medicamentosas / Inibidores da Fosfodiesterase 5 / Rilpivirina / Tadalafila Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasma / Midazolam / Fármacos Anti-HIV / Interações Medicamentosas / Inibidores da Fosfodiesterase 5 / Rilpivirina / Tadalafila Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article