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TALEN-Mediated Inactivation of PD-1 in Tumor-Reactive Lymphocytes Promotes Intratumoral T-cell Persistence and Rejection of Established Tumors.
Menger, Laurie; Sledzinska, Anna; Bergerhoff, Katharina; Vargas, Frederick Arce; Smith, Julianne; Poirot, Laurent; Pule, Martin; Hererro, Javier; Peggs, Karl S; Quezada, Sergio A.
Afiliação
  • Menger L; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom.
  • Sledzinska A; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom.
  • Bergerhoff K; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom.
  • Vargas FA; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom.
  • Smith J; Cellectis, Paris, France.
  • Poirot L; Cellectis, Paris, France.
  • Pule M; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom.
  • Hererro J; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom. Bill Lyons Informatics Centre, University College London Cancer Institute, London, United Kingdom.
  • Peggs KS; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom. s.quezada@ucl.ac.uk Karl.Peggs@ucl.ac.uk.
  • Quezada SA; Cancer Immunology Unit, Research Department of Hematology, University College London Cancer Institute, London, United Kingdom. s.quezada@ucl.ac.uk Karl.Peggs@ucl.ac.uk.
Cancer Res ; 76(8): 2087-93, 2016 04 15.
Article em En | MEDLINE | ID: mdl-27197251
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos do Interstício Tumoral / Receptor de Morte Celular Programada 1 Tipo de estudo: Guideline Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos do Interstício Tumoral / Receptor de Morte Celular Programada 1 Tipo de estudo: Guideline Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article