Developmental Origins of Common Disease: Epigenetic Contributions to Obesity.
Annu Rev Genomics Hum Genet
; 17: 177-92, 2016 08 31.
Article
em En
| MEDLINE
| ID: mdl-27216778
ABSTRACT
The perinatal period is a window of susceptibility for later life disease. Recent epigenetic findings are beginning to increase our understanding of the molecular mechanisms that may contribute to the programming of obesity. This review summarizes recent evidence that supports the role of epigenetically mediated early life programming in the later onset of obesity. Establishing such links between environmental exposures and modifiable molecular changes ultimately holds promise to inform interventional efforts toward alleviating the environmentally mediated onset of obesity.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Predisposição Genética para Doença
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Epigenômica
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Interação Gene-Ambiente
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Obesidade
Tipo de estudo:
Etiology_studies
Limite:
Female
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Humans
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Pregnancy
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article