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High prevalence of diffuse large B-cell lymphoma in occult hepatitis B virus-infected patients in the Tohoku district in Eastern Japan.
Tajima, Katsushi; Takahashi, Naoto; Ishizawa, Kenichi; Murai, Kazunori; Akagi, Tomoaki; Noji, Hideyoshi; Sasaki, Osamu; Wano, Masaharu; Itoh, Jugoh; Kato, Yuichi; Scichishima, Tsutomu; Ishida, Yoji; Harigae, Hideo; Sawada, Kenichi.
Afiliação
  • Tajima K; Department of Radiation Emergency Medicine, National Institute of Radiological Sciences, Chiba, Japan. tajima@nirs.go.jp.
  • Takahashi N; Department of Neurology, Hematology, Metabolism, Endocrinology, and Diabetology (DNHMED), Yamagata University School of Medicine, Yamagata, Japan. tajima@nirs.go.jp.
  • Ishizawa K; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
  • Murai K; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Akagi T; Department of Hematology/Oncology, Internal Medicine, Iwate Medical University, Morioka, Japan.
  • Noji H; Department of Hematology, Aomori Prefectural Central Hospital, Aomori, Japan.
  • Sasaki O; Department of Cardiology and Hematology, Fukushima Medical University, Fukushima, Japan.
  • Wano M; Division of Hematology, Department of Internal Medicine, Miyagi Cancer Center, Natori, Japan.
  • Itoh J; Department of Hematology, Iwate Prefectural Central Hospital, Morioka, Japan.
  • Kato Y; Department of Medical Oncology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
  • Scichishima T; Department of Neurology, Hematology, Metabolism, Endocrinology, and Diabetology (DNHMED), Yamagata University School of Medicine, Yamagata, Japan.
  • Ishida Y; Department of Cardiology and Hematology, Fukushima Medical University, Fukushima, Japan.
  • Harigae H; Department of Hematology/Oncology, Internal Medicine, Iwate Medical University, Morioka, Japan.
  • Sawada K; Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
J Med Virol ; 88(12): 2206-2210, 2016 12.
Article em En | MEDLINE | ID: mdl-27219865
Occult hepatitis B virus (HBV) infection is a clinical challenge, but its relationship to clinicopathologic features and the risk of progression to malignant lymphoma (ML) are poorly defined. We estimated the prevalence of HBV infection of 1,358 patients with newly diagnosed ML. HBV infection was more prevalent in ML than in control patients. The occult HBV infection group had a higher median onset age, no liver or spleen involvement, and higher prevalence of diffuse large B-cell lymphoma than the other groups, indicating that occult HBV infection is a distinct clinicopathologic entity. J. Med. Virol. 88:2206-2210, 2016. © 2016 Wiley Periodicals, Inc.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma Difuso de Grandes Células B / Infecções Assintomáticas / Hepatite B / Linfoma Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma Difuso de Grandes Células B / Infecções Assintomáticas / Hepatite B / Linfoma Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2016 Tipo de documento: Article