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Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes.
MacDonald, Douglas A; Martin, Joel; Muthusamy, Kathir K; Luo, Jiann-Kae; Pyles, Erica; Rafique, Ashique; Huang, Tammy; Potocky, Terra; Liu, Yang; Cao, Jingtai; Bono, Françoise; Delesque, Nathalie; Savi, Pierre; Francis, John; Amirkhosravi, Ali; Meyer, Todd; Romano, Carmelo; Glinka, Meredith; Yancopoulos, George D; Stahl, Neil; Wiegand, Stanley J; Papadopoulos, Nicholas.
Afiliação
  • MacDonald DA; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Martin J; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Muthusamy KK; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Luo JK; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Pyles E; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Rafique A; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Huang T; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Potocky T; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Liu Y; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Cao J; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Bono F; Sanofi, Toulouse, France.
  • Delesque N; Sanofi, Toulouse, France.
  • Savi P; Sanofi, Toulouse, France.
  • Francis J; Center for Thrombosis Research, Florida Hospital, Orlando, FL, USA.
  • Amirkhosravi A; Center for Thrombosis Research, Florida Hospital, Orlando, FL, USA.
  • Meyer T; Center for Thrombosis Research, Florida Hospital, Orlando, FL, USA.
  • Romano C; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Glinka M; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Yancopoulos GD; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Stahl N; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Wiegand SJ; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Papadopoulos N; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA. nicholas.papadopoulos@regeneron.com.
Angiogenesis ; 19(3): 389-406, 2016 07.
Article em En | MEDLINE | ID: mdl-27234973
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Receptores de Fatores de Crescimento do Endotélio Vascular / Fator A de Crescimento do Endotélio Vascular / Bevacizumab Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Receptores de Fatores de Crescimento do Endotélio Vascular / Fator A de Crescimento do Endotélio Vascular / Bevacizumab Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article