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Autophagy degrades hypoxia inducible factors.
DePavia, Adela; Jonasch, Eric; Liu, Xian-De.
Afiliação
  • DePavia A; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.
  • Jonasch E; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.
  • Liu XD; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.
Mol Cell Oncol ; 3(2): e1104428, 2016 Mar.
Article em En | MEDLINE | ID: mdl-27308629
Hypoxia inducible factors are subjected to degradation by the ubiquitin-proteasome system (UPS), macroautophagy, and chaperone-mediated autophagy. The E3 ligases, ubiquitination, autophagy receptor proteins, and oxygen are determinants that direct hypoxia-inducible factors to different degradation pathways.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article