Risk of stroke among patients with cerebral palsy: a population-based cohort study.
Dev Med Child Neurol
; 59(1): 52-56, 2017 01.
Article
em En
| MEDLINE
| ID: mdl-27346658
ABSTRACT
AIM:
The aim of the study was to investigate the risk of stroke in patients with cerebral palsy (CP), based on nationwide data in Taiwan.METHOD:
This prospective cohort study was comprised of patients recorded on the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005) who had a diagnosis of CP (n=1975) in records between 1 January 2004 and 31 December 2007. A comparison group (15) drawn from the same database was matched for age and sex (n=9875). Each patient was tracked by data until the development of stroke or the end of 2008. Cox proportional-hazards regression analysis was used to evaluate the hazard ratios after adjusting for potential confounding factors.RESULTS:
Patients with CP were more likely to suffer stroke than the comparison population, after adjusting for potential confounding factors (adjusted hazard ratio 2.17; 95% confidence interval [CI] 1.74-2.69). The hazard ratio of stroke was 4.78 (95% CI 3.18-7.17) and 1.57 (95% CI 1.20-2.05) for patients with CP aged 50 years and under, and over 50 years respectively.INTERPRETATION:
Cerebral palsy is a risk factor or marker for stroke that is independent of traditional stroke risk factors. Further research in this area is warranted.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paralisia Cerebral
/
Acidente Vascular Cerebral
Tipo de estudo:
Etiology_studies
/
Incidence_studies
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Observational_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article