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A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor.
Takano, Akihiro; Stenkrona, Per; Stepanov, Vladimir; Amini, Nahid; Martinsson, Stefan; Tsai, Max; Goldsmith, Paul; Xie, Jinhui; Wu, Jingtao; Uz, Tolga; Halldin, Christer; Macek, Thomas A.
Afiliação
  • Takano A; Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden. Electronic address: akihiro.takano@ki.se.
  • Stenkrona P; Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden.
  • Stepanov V; Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden.
  • Amini N; Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden.
  • Martinsson S; Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden.
  • Tsai M; Takeda Development Center Americas, Inc., Deerfield, IL, USA.
  • Goldsmith P; Takeda Development Centre Europe, London, UK.
  • Xie J; Takeda Development Center Americas, Inc., Deerfield, IL, USA.
  • Wu J; Takeda Development Center Americas, Inc., Deerfield, IL, USA.
  • Uz T; Takeda Development Center Americas, Inc., Deerfield, IL, USA.
  • Halldin C; Karolinska Institutet, Department of Clinical Neuroscience, Center for Psychiatric Research, Stockholm, Sweden.
  • Macek TA; Takeda Development Center Americas, Inc., Deerfield, IL, USA.
Neuroimage ; 141: 10-17, 2016 Nov 01.
Article em En | MEDLINE | ID: mdl-27423256
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Piridazinas / Encéfalo / Diester Fosfórico Hidrolases / Imagem Molecular Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Piridazinas / Encéfalo / Diester Fosfórico Hidrolases / Imagem Molecular Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article