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Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification.
Lee, So Yeon; Kim, Kyoung-Ran; Bang, Duhee; Bae, Se Won; Kim, Hak Joong; Ahn, Dae-Ro.
Afiliação
  • Lee SY; The Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. drahn@kist.re.kr and Department of Chemistry, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, Republic of Korea.
  • Kim KR; The Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. drahn@kist.re.kr and Department of Chemistry, College of Science, Yonsei University, Seoul, Republic of Korea.
  • Bang D; Department of Chemistry, College of Science, Yonsei University, Seoul, Republic of Korea.
  • Bae SW; Green Materials and Process Group, Korea Institute of Industrial Technology, Cheonan, Chungnam 31056, Republic of Korea.
  • Kim HJ; Department of Chemistry, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, Republic of Korea.
  • Ahn DR; The Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. drahn@kist.re.kr and Department of Biological Chemistry, KIST campus, University of Science and Technology (UST), Republic o
Biomater Sci ; 4(9): 1314-7, 2016 Aug 16.
Article em En | MEDLINE | ID: mdl-27464359
ABSTRACT
Although rolling circle amplification (RCA) is an efficient method to produce DNA materials for biomedical applications, it does not yield nano-sized products suitable for intracellular delivery. We here provide the ways to control the size of RCA products and show a potential application of the size-controlled DNA nanoparticles.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Técnicas de Amplificação de Ácido Nucleico / Nanopartículas Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Técnicas de Amplificação de Ácido Nucleico / Nanopartículas Idioma: En Ano de publicação: 2016 Tipo de documento: Article