Upregulation of miR-192 inhibits cell growth and invasion and induces cell apoptosis by targeting TCF7 in human osteosarcoma.

Wang, Yadong; Zhang, Shanfeng; Xu, Yan; Zhang, Yan; Guan, Hongya; Li, Xinjie; Li, Yuebai; Wang, Yisheng

Wang, Yadong; Zhang, Shanfeng; Xu, Yan; Zhang, Yan; Guan, Hongya; Li, Xinjie; Li, Yuebai; Wang, Yisheng.

Afiliação

Wang Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhengzhou University, 100 Kexue Road, Zhengzhou, 450001, China.
Zhang S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhengzhou University, 100 Kexue Road, Zhengzhou, 450001, China.
Xu Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhengzhou University, 100 Kexue Road, Zhengzhou, 450001, China.
Zhang Y; Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, China.
Guan H; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhengzhou University, 100 Kexue Road, Zhengzhou, 450001, China.
Li X; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhengzhou University, 100 Kexue Road, Zhengzhou, 450001, China.
Li Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhengzhou University, 100 Kexue Road, Zhengzhou, 450001, China. liyuebai@zzu.edu.cn.
Wang Y; Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, China.

Tumour Biol ; 37(11): 15211-15220, 2016 Nov.

Article em En | MEDLINE | ID: mdl-27683056

Assuntos

Neoplasias Ósseas/patologia; Movimento Celular; Proliferação de Células; Regulação Neoplásica da Expressão Gênica; MicroRNAs/genética; Osteossarcoma/patologia; Fator 1 de Transcrição de Linfócitos T/metabolismo; Apoptose; Neoplasias Ósseas/genética; Neoplasias Ósseas/metabolismo; Osso e Ossos/metabolismo; Osso e Ossos/patologia; Estudos de Casos e Controles; Humanos; Invasividade Neoplásica; Osteossarcoma/genética; Osteossarcoma/metabolismo; RNA Mensageiro/genética; Reação em Cadeia da Polimerase em Tempo Real; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Fator 1 de Transcrição de Linfócitos T/genética; Células Tumorais Cultivadas

Palavras-chave

Apoptosis; Invasion; Osteosarcoma; Proliferation; TCF7; miR-192

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Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma / Regulação Neoplásica da Expressão Gênica / Movimento Celular / MicroRNAs / Proliferação de Células / Fator 1 de Transcrição de Linfócitos T Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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