Five new lactone derivatives from the stems of Dendrobium nobile.
Fitoterapia
; 115: 96-100, 2016 Dec.
Article
em En
| MEDLINE
| ID: mdl-27720924
Five new lactone derivatives decumbic acids A and B (1 and 2), (-)-decumbic acid (3a), (-)- and (+)-dendrolactone (4a and 4b) together with four known compounds (3b and 5-7) were isolated from the stems of Dendrobium nobile. Their structures were elucidated using comprehensive spectroscopic methods. Compounds 3a and 3b, 4a and 4b were isolated as two pair of enantiomers by chiral HPLC. The absolute configurations of 1, 2, 3a, 4a and 4b were determined by optical rotation and X-ray crystallographic analysis. The inhibitory activities of all compounds against nine phytopathogenic fungi and three cancer cell lines were evaluated.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Caules de Planta
/
Dendrobium
/
Lactonas
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article