mTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections.

Fang, Lijun; Tu, Huaijun; Guo, Wei; Wang, Shixuan; Xue, Ting; Yang, Fei; Zhang, Xiaoyan; Yang, Yazhi; Wan, Qian; Shi, Zhexin; Zhan, Xulong; Li, Jian

Fang, Lijun; Tu, Huaijun; Guo, Wei; Wang, Shixuan; Xue, Ting; Yang, Fei; Zhang, Xiaoyan; Yang, Yazhi; Wan, Qian; Shi, Zhexin; Zhan, Xulong; Li, Jian.

Afiliação

Fang L; Department of Hematology, The Second Affiliated Hospital of Nanchang University, Key Laboratory of Experimental Hematology in Jiangxi Province, Nanchang, Jiangxi, China; Medical Department of Nanchang University Graduate School, Nanchang, Jiangxi, China.
Tu H; Department of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Guo W; State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Disease, Chinese Academy of Medical Sciences, Tianjin, China.
Wang S; State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Disease, Chinese Academy of Medical Sciences, Tianjin, China.
Xue T; Department of Medical Microbiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yang F; State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Disease, Chinese Academy of Medical Sciences, Tianjin, China.
Zhang X; Department of Hematology, The Second Affiliated Hospital of Nanchang University, Key Laboratory of Experimental Hematology in Jiangxi Province, Nanchang, Jiangxi, China; Medical Department of Nanchang University Graduate School, Nanchang, Jiangxi, China.
Yang Y; Department of Hematology, The Second Affiliated Hospital of Nanchang University, Key Laboratory of Experimental Hematology in Jiangxi Province, Nanchang, Jiangxi, China; Medical Department of Nanchang University Graduate School, Nanchang, Jiangxi, China.
Wan Q; Department of Hematology, The Second Affiliated Hospital of Nanchang University, Key Laboratory of Experimental Hematology in Jiangxi Province, Nanchang, Jiangxi, China; Medical Department of Nanchang University Graduate School, Nanchang, Jiangxi, China.
Shi Z; Department of Hematology and Oncology, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhan X; Department of Hematology, The Second Affiliated Hospital of Nanchang University, Key Laboratory of Experimental Hematology in Jiangxi Province, Nanchang, Jiangxi, China; Medical Department of Nanchang University Graduate School, Nanchang, Jiangxi, China.
Li J; Department of Hematology, The Second Affiliated Hospital of Nanchang University, Key Laboratory of Experimental Hematology in Jiangxi Province, Nanchang, Jiangxi, China.

Mediators Inflamm ; 2016: 7369351, 2016.

Article em En | MEDLINE | ID: mdl-27746591

Assuntos

Infecções Bacterianas/imunologia; Infecções Bacterianas/metabolismo; Monócitos/imunologia; Monócitos/metabolismo; Complexos Multiproteicos/metabolismo; Linfócitos T Reguladores/imunologia; Serina-Treonina Quinases TOR/metabolismo; Animais; Escherichia coli/imunologia; Escherichia coli/patogenicidade; Feminino; Interleucina-1/metabolismo; Interleucina-10/metabolismo; Interleucina-6/metabolismo; Masculino; Alvo Mecanístico do Complexo 1 de Rapamicina; Camundongos; Camundongos Knockout; Complexos Multiproteicos/líquido cefalorraquidiano; Complexos Multiproteicos/genética; Serina-Treonina Quinases TOR/líquido cefalorraquidiano; Serina-Treonina Quinases TOR/genética; Fator de Crescimento Transformador beta/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Monócitos / Linfócitos T Reguladores / Complexos Multiproteicos / Serina-Treonina Quinases TOR Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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