Your browser doesn't support javascript.
loading
Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.
Roszik, Jason; Haydu, Lauren E; Hess, Kenneth R; Oba, Junna; Joon, Aron Y; Siroy, Alan E; Karpinets, Tatiana V; Stingo, Francesco C; Baladandayuthapani, Veera; Tetzlaff, Michael T; Wargo, Jennifer A; Chen, Ken; Forget, Marie-Andrée; Haymaker, Cara L; Chen, Jie Qing; Meric-Bernstam, Funda; Eterovic, Agda K; Shaw, Kenna R; Mills, Gordon B; Gershenwald, Jeffrey E; Radvanyi, Laszlo G; Hwu, Patrick; Futreal, P Andrew; Gibbons, Don L; Lazar, Alexander J; Bernatchez, Chantale; Davies, Michael A; Woodman, Scott E.
Afiliação
  • Roszik J; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 904, Houston, TX, 77030, USA. jroszik@mdanderson.org.
  • Haydu LE; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. jroszik@mdanderson.org.
  • Hess KR; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Oba J; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Joon AY; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 904, Houston, TX, 77030, USA.
  • Siroy AE; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Karpinets TV; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Stingo FC; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Baladandayuthapani V; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Tetzlaff MT; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wargo JA; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Chen K; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Forget MA; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Haymaker CL; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Chen JQ; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 904, Houston, TX, 77030, USA.
  • Meric-Bernstam F; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 904, Houston, TX, 77030, USA.
  • Eterovic AK; Lion Biotechnologies, Woodland Hills, CA, 91637, USA.
  • Shaw KR; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Mills GB; Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, 770393, USA.
  • Gershenwald JE; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Radvanyi LG; Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, 770393, USA.
  • Hwu P; Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, 770393, USA.
  • Futreal PA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Gibbons DL; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Lazar AJ; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Bernatchez C; EMD Serono, Rockland, MA, 02370, USA.
  • Davies MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 904, Houston, TX, 77030, USA.
  • Woodman SE; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
BMC Med ; 14(1): 168, 2016 10 25.
Article em En | MEDLINE | ID: mdl-27776519

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Adenocarcinoma / Imunoterapia / Neoplasias Pulmonares / Melanoma / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Adenocarcinoma / Imunoterapia / Neoplasias Pulmonares / Melanoma / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article