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Identification of the minimum PAR4 inhibitor pharmacophore and optimization of a series of 2-methoxy-6-arylimidazo[2,1-b][1,3,4]thiadiazoles.
Temple, Kayla J; Duvernay, Matthew T; Maeng, Jae G; Blobaum, Anna L; Stauffer, Shaun R; Hamm, Heidi E; Lindsley, Craig W.
Afiliação
  • Temple KJ; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Duvernay MT; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Maeng JG; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Blobaum AL; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Stauffer SR; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Hamm HE; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Lindsley CW; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Bioorg Med Chem Lett ; 26(22): 5481-5486, 2016 11 15.
Article em En | MEDLINE | ID: mdl-27777004
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiadiazóis / Agregação Plaquetária / Receptores de Trombina Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiadiazóis / Agregação Plaquetária / Receptores de Trombina Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article