Screening and Characterization of a Non-cyp51A Mutation in an Aspergillus fumigatus cox10 Strain Conferring Azole Resistance.

Wei, Xiaolei; Chen, Peiying; Gao, Rongsui; Li, Yeqi; Zhang, Anxue; Liu, Feifei; Lu, Ling

Wei, Xiaolei; Chen, Peiying; Gao, Rongsui; Li, Yeqi; Zhang, Anxue; Liu, Feifei; Lu, Ling.

Afiliação

Wei X; Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Chen P; Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Gao R; Department of Dermatology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Li Y; Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Zhang A; Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Liu F; Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Lu L; Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, China.

Antimicrob Agents Chemother ; 61(1)2017 01.

Article em En | MEDLINE | ID: mdl-27799210

Assuntos

Aspergillus fumigatus/efeitos dos fármacos; Farmacorresistência Fúngica/genética; Farnesiltranstransferase/genética; Proteínas Fúngicas/genética; Mutação; Antifúngicos/farmacologia; Aspergillus fumigatus/genética; Aspergillus fumigatus/crescimento & desenvolvimento; Aspergillus fumigatus/metabolismo; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/metabolismo; Farnesiltranstransferase/metabolismo; Proteínas Fúngicas/metabolismo; Expressão Gênica; Teste de Complementação Genética; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Itraconazol/farmacologia; Polimorfismo de Nucleotídeo Único

Palavras-chave

Aspergillus fumigatus; azole resistance; cox10; cyp51A; mutation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aspergillus fumigatus / Proteínas Fúngicas / Farmacorresistência Fúngica / Farnesiltranstransferase / Mutação Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google