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Inhibition of RAS function through targeting an allosteric regulatory site.
Spencer-Smith, Russell; Koide, Akiko; Zhou, Yong; Eguchi, Raphael R; Sha, Fern; Gajwani, Priyanka; Santana, Dianicha; Gupta, Ankit; Jacobs, Miranda; Herrero-Garcia, Erika; Cobbert, Jacqueline; Lavoie, Hugo; Smith, Matthew; Rajakulendran, Thanashan; Dowdell, Evan; Okur, Mustafa Nazir; Dementieva, Irina; Sicheri, Frank; Therrien, Marc; Hancock, John F; Ikura, Mitsuhiko; Koide, Shohei; O'Bryan, John P.
Afiliação
  • Spencer-Smith R; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Koide A; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Zhou Y; Jesse Brown VA Medical Center, Chicago, Illinois, USA.
  • Eguchi RR; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
  • Sha F; Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York, USA.
  • Gajwani P; Department of Medicine, New York University Langone Medical Center, New York, New York, USA.
  • Santana D; Department of Integrative Biology and Pharmacology, University of Texas Medical School at Houston, Houston, Texas, USA.
  • Gupta A; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
  • Jacobs M; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
  • Herrero-Garcia E; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Cobbert J; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Lavoie H; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Smith M; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Rajakulendran T; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
  • Dowdell E; Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York, USA.
  • Okur MN; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Dementieva I; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Sicheri F; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Therrien M; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Hancock JF; Jesse Brown VA Medical Center, Chicago, Illinois, USA.
  • Ikura M; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Koide S; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA.
  • O'Bryan JP; Institute for Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montreal, Quebec, Canada.
Nat Chem Biol ; 13(1): 62-68, 2017 Jan.
Article em En | MEDLINE | ID: mdl-27820802
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas ras / Sítio Alostérico / Anticorpos Monoclonais Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas ras / Sítio Alostérico / Anticorpos Monoclonais Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article