Structural assemblies of the di- and oligomeric G-protein coupled receptor TGR5 in live cells: an MFIS-FRET and integrative modelling study.

Greife, Annemarie; Felekyan, Suren; Ma, Qijun; Gertzen, Christoph G W; Spomer, Lina; Dimura, Mykola; Peulen, Thomas O; Wöhler, Christina; Häussinger, Dieter; Gohlke, Holger; Keitel, Verena; Seidel, Claus A M

Greife, Annemarie; Felekyan, Suren; Ma, Qijun; Gertzen, Christoph G W; Spomer, Lina; Dimura, Mykola; Peulen, Thomas O; Wöhler, Christina; Häussinger, Dieter; Gohlke, Holger; Keitel, Verena; Seidel, Claus A M.

Afiliação

Greife A; Chair for Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Felekyan S; Chair for Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Ma Q; Chair for Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Gertzen CG; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Spomer L; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Dimura M; Chair for Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Peulen TO; Chair for Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Wöhler C; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Häussinger D; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Gohlke H; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Keitel V; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Seidel CA; Chair for Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.

Sci Rep ; 6: 36792, 2016 11 11.

Article em En | MEDLINE | ID: mdl-27833095

Assuntos

Multimerização Proteica; Receptores Acoplados a Proteínas G/metabolismo; Substituição de Aminoácidos; Animais; Cães; Transferência Ressonante de Energia de Fluorescência; Proteínas de Fluorescência Verde/genética; Proteínas de Fluorescência Verde/metabolismo; Células HEK293; Humanos; Células Madin Darby de Rim Canino; Modelos Moleculares; Estrutura Quaternária de Proteína; Transporte Proteico; Receptores Acoplados a Proteínas G/genética; Proteínas Recombinantes de Fusão/genética; Proteínas Recombinantes de Fusão/metabolismo; Análise de Célula Única; Espectrometria de Fluorescência

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Acoplados a Proteínas G / Multimerização Proteica Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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