CXCR4 antagonists suppress small cell lung cancer progression.

Taromi, Sanaz; Kayser, Gian; Catusse, Julie; von Elverfeldt, Dominik; Reichardt, Wilfried; Braun, Friederike; Weber, Wolfgang A; Zeiser, Robert; Burger, Meike

Taromi, Sanaz; Kayser, Gian; Catusse, Julie; von Elverfeldt, Dominik; Reichardt, Wilfried; Braun, Friederike; Weber, Wolfgang A; Zeiser, Robert; Burger, Meike.

Afiliação

Taromi S; Department of Medicine, Division of Hematology/Oncology, University Medical Center, Hugstetter, D-79106 Freiburg, Germany.
Kayser G; Department of Pathology, University Medical Center, Breisacher, D-79106 Freiburg.
Catusse J; Department of Medicine, Division of Hematology/Oncology, University Medical Center, Hugstetter, D-79106 Freiburg, Germany.
von Elverfeldt D; Department of Radiology Medical Physics, University Medical Center, Breisacher, D-79106 Freiburg.
Reichardt W; Department of Radiology Medical Physics, University Medical Center, Breisacher, D-79106 Freiburg.
Braun F; Institute of Nuclear Medicine, University Medical Center, Hugstetter D-79106 Freiburg, Germany.
Weber WA; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York 10065, NY, USA.
Zeiser R; University of Freiburg, Faculty of Biology, Schaenzlestrasse, D-79106 Freiburg, Germany.
Burger M; Institute of Nuclear Medicine, University Medical Center, Hugstetter D-79106 Freiburg, Germany.

Oncotarget ; 7(51): 85185-85195, 2016 Dec 20.

Article em En | MEDLINE | ID: mdl-27835905

Assuntos

Compostos Heterocíclicos/uso terapêutico; Neoplasias Pulmonares/tratamento farmacológico; Peptídeos/uso terapêutico; Receptores CXCR4/antagonistas & inibidores; Carcinoma de Pequenas Células do Pulmão/tratamento farmacológico; Animais; Benzilaminas; Carcinogênese; Linhagem Celular Tumoral; Movimento Celular; Cisplatino/uso terapêutico; Ciclamos; Proteínas de Ligação a DNA/genética; Resistencia a Medicamentos Antineoplásicos; Etoposídeo/uso terapêutico; Compostos Heterocíclicos/farmacologia; Humanos; Camundongos; Camundongos Knockout; Metástase Neoplásica; Proteínas Nucleares/genética; Peptídeos/farmacologia; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

AMD3100; CXCL12; metastasis; mouse model; small cell lung cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Receptores CXCR4 / Carcinoma de Pequenas Células do Pulmão / Compostos Heterocíclicos / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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