Membrane Recruitment of the Non-receptor Protein GIV/Girdin (G&#945;-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling.

Parag-Sharma, Kshitij; Leyme, Anthony; DiGiacomo, Vincent; Marivin, Arthur; Broselid, Stefan; Garcia-Marcos, Mikel

Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling.

Parag-Sharma, Kshitij; Leyme, Anthony; DiGiacomo, Vincent; Marivin, Arthur; Broselid, Stefan; Garcia-Marcos, Mikel.

Afiliação

Parag-Sharma K; From the Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
Leyme A; From the Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
DiGiacomo V; From the Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
Marivin A; From the Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
Broselid S; From the Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
Garcia-Marcos M; From the Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118 mgm1@bu.edu.

J Biol Chem ; 291(53): 27098-27111, 2016 12 30.

Article em En | MEDLINE | ID: mdl-27864364

Assuntos

Membrana Celular/metabolismo; Proteínas Heterotriméricas de Ligação ao GTP/metabolismo; Microdomínios da Membrana/metabolismo; Proteínas dos Microfilamentos/metabolismo; Saccharomyces cerevisiae/metabolismo; Proteínas de Transporte Vesicular/metabolismo; Células HeLa; Proteínas Heterotriméricas de Ligação ao GTP/genética; Humanos; Immunoblotting; Proteínas dos Microfilamentos/genética; Saccharomyces cerevisiae/genética; Proteínas de Transporte Vesicular/genética

Palavras-chave

G protein-coupled receptor (GPCR); bioluminescence resonance energy transfer (BRET); guanine nucleotide exchange factor (GEF); heterotrimeric G protein; receptor tyrosine kinase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Membrana Celular / Proteínas Heterotriméricas de Ligação ao GTP / Microdomínios da Membrana / Proteínas de Transporte Vesicular / Proteínas dos Microfilamentos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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