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The 5-HT1A/1B-receptor agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and decreases motivation for reward and "waiting" impulsivity, but increases "stopping" impulsivity.
Korte, S Mechiel; Prins, Jolanda; Van den Bergh, Filip S; Oosting, Ronald S; Dupree, Rudy; Korte-Bouws, Gerdien A H; Westphal, Koen G C; Olivier, Berend; Denys, Damiaan A; Garland, Alexis; Güntürkün, Onur.
Afiliação
  • Korte SM; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, The Netherlands; Department of Biopsychology, Institute of Cognitive Neuroscience, Faculty of Psychology, Ruhr-University Bochum, Germany. Electronic address: s.m.korte@uu.nl.
  • Prins J; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, The Netherlands.
  • Van den Bergh FS; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, The Netherlands.
  • Oosting RS; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, The Netherlands.
  • Dupree R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, The Netherlands.
  • Korte-Bouws GA; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, The Netherlands.
  • Westphal KG; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, The Netherlands.
  • Olivier B; Groningen Institute for Evolutionary Life Sciences, University of Groningen, The Netherlands.
  • Denys DA; Department of Psychiatry, Academic Medical Center, University of Amsterdam, The Netherlands.
  • Garland A; Department of Biopsychology, Institute of Cognitive Neuroscience, Faculty of Psychology, Ruhr-University Bochum, Germany.
  • Güntürkün O; Department of Biopsychology, Institute of Cognitive Neuroscience, Faculty of Psychology, Ruhr-University Bochum, Germany.
Eur J Pharmacol ; 794: 257-269, 2017 Jan 05.
Article em En | MEDLINE | ID: mdl-27866999
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Dopamina / Córtex Pré-Frontal / Agonistas do Receptor 5-HT1 de Serotonina / Comportamento Impulsivo / Motivação / Núcleo Accumbens Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Dopamina / Córtex Pré-Frontal / Agonistas do Receptor 5-HT1 de Serotonina / Comportamento Impulsivo / Motivação / Núcleo Accumbens Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article