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Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.
Döhner, Hartmut; Estey, Elihu; Grimwade, David; Amadori, Sergio; Appelbaum, Frederick R; Büchner, Thomas; Dombret, Hervé; Ebert, Benjamin L; Fenaux, Pierre; Larson, Richard A; Levine, Ross L; Lo-Coco, Francesco; Naoe, Tomoki; Niederwieser, Dietger; Ossenkoppele, Gert J; Sanz, Miguel; Sierra, Jorge; Tallman, Martin S; Tien, Hwei-Fang; Wei, Andrew H; Löwenberg, Bob; Bloomfield, Clara D.
Afiliação
  • Döhner H; Department of Internal Medicine III, University of Ulm, Ulm, Germany.
  • Estey E; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
  • Grimwade D; Department of Medical and Molecular Genetics, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
  • Amadori S; Department of Biomedicine and Prevention, Università di Roma "Tor Vergata," Rome, Italy.
  • Appelbaum FR; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
  • Büchner T; Department of Hematology/Oncology, University of Münster, Münster, Germany.
  • Dombret H; Institut Universitaire d'Hématologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
  • Ebert BL; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Fenaux P; Service d'Hématologie, Hôpital Saint-Louis, Paris, France.
  • Larson RA; Department of Medicine, University of Chicago, Chicago, IL.
  • Levine RL; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Lo-Coco F; Department of Biomedicine and Prevention, Università di Roma "Tor Vergata," Rome, Italy.
  • Naoe T; National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
  • Niederwieser D; Department of Hematology, Oncology and Hemostasis, University of Leipzig, Leipzig, Germany.
  • Ossenkoppele GJ; Department of Haematology, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands.
  • Sanz M; Department of Hematology, University Hospital La Fe, University of Valencia, Valencia, Spain.
  • Sierra J; Hematology Department, Hospital de la Santa Creu i Sant Pau, Jose Carreras Leukemia Research Institute, Barcelona, Spain.
  • Tallman MS; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Tien HF; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
  • Wei AH; Department of Clinical Hematology, The Alfred Hospital, Melbourne, Australia.
  • Löwenberg B; Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.
  • Bloomfield CD; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands; and.
Blood ; 129(4): 424-447, 2017 01 26.
Article em En | MEDLINE | ID: mdl-27895058
ABSTRACT
The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults, published in 2010, has found broad acceptance by physicians and investigators caring for patients with AML. Recent advances, for example, in the discovery of the genomic landscape of the disease, in the development of assays for genetic testing and for detecting minimal residual disease (MRD), as well as in the development of novel antileukemic agents, prompted an international panel to provide updated evidence- and expert opinion-based recommendations. The recommendations include a revised version of the ELN genetic categories, a proposal for a response category based on MRD status, and criteria for progressive disease.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transplante de Células-Tronco Hematopoéticas / Gerenciamento Clínico / Antineoplásicos Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transplante de Células-Tronco Hematopoéticas / Gerenciamento Clínico / Antineoplásicos Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article