Amino acid sequence of the crustacean hyperglycemic hormone (CHH) from the shore crab, Carcinus maenas.

ABSTRACT

Crustacean hyperglycemic hormone (CHH) was isolated from sinus glands of Carcinus maenas, and its primary structure was determined by manual microsequencing, using the DABITC-PITC double-coupling method. The neurohormone consists of 72 amino acid residues (8524 Da). Three disulfide bridges are present and both the N- and C-terminus are blocked. CHH does not show significant sequence homology to any known peptide hormone or protein.