HDAC10 as a potential therapeutic target in ovarian cancer.

Islam, Muhtadi M; Banerjee, Tapahsama; Packard, Colin Z; Kotian, Shweta; Selvendiran, Karuppaiyah; Cohn, David E; Parvin, Jeffrey D

Islam, Muhtadi M; Banerjee, Tapahsama; Packard, Colin Z; Kotian, Shweta; Selvendiran, Karuppaiyah; Cohn, David E; Parvin, Jeffrey D.

Afiliação

Islam MM; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, United States.
Banerjee T; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, United States.
Packard CZ; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, United States.
Kotian S; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, United States.
Selvendiran K; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, United States.
Cohn DE; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, United States.
Parvin JD; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, United States. Electronic address: Jeffrey.Parvin@osumc.edu.

Gynecol Oncol ; 144(3): 613-620, 2017 03.

Article em En | MEDLINE | ID: mdl-28073598

Assuntos

Histona Desacetilases/genética; Histona Desacetilases/metabolismo; Neoplasias Ovarianas/enzimologia; Neoplasias Ovarianas/genética; Linhagem Celular Tumoral; Cisplatino/farmacologia; Feminino; Células HeLa; Inibidores de Histona Desacetilases/farmacologia; Humanos; Terapia de Alvo Molecular; Neoplasias Ovarianas/tratamento farmacológico; Neoplasias Ovarianas/patologia; RNA Mensageiro/biossíntese; RNA Mensageiro/genética; Reparo de DNA por Recombinação/efeitos dos fármacos

Palavras-chave

Cisplatin; DNA repair; HDAC10; Ovarian cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Histona Desacetilases Limite: Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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