Skin-to-skin contact after birth and the natural course of neurosteroid levels in healthy term newborns.
J Perinatol
; 37(5): 591-595, 2017 05.
Article
em En
| MEDLINE
| ID: mdl-28102853
ABSTRACT
OBJECTIVE:
To determine the postnatal course of neurosteroid levels in relation to gender, mode of delivery and the extent of skin-to-skin (STS) contact during the first days of life in healthy term newborns. STUDYDESIGN:
Prospective observational study of 39 neonates in which parents recorded total duration of STS in the first 2 days and nine neurosteroids (dehydroepiandrosterone-sulfate, progesterone, pregnenolone, pregnenolone-sulfate, allopregnanolone, isopregnanolone, epipregnanolone, pregnanolone and pregnanolone-sulfate) were assayed from blood samples at birth and at 1-2 days of age.RESULTS:
All nine neurosteroid levels declined significantly during the first 2 days of life. Gender did not significantly affect the change in neurosteroid levels. The decline in neurosteroid levels was generally more pronounced in vaginal deliveries, and there was a trend toward a larger decline with more exposure to STS.CONCLUSION:
Ongoing studies may better characterize the role of neurosteroids and the influence of STS in more critically ill and premature neonates.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tato
/
Neurotransmissores
/
Nascimento a Termo
/
Método Canguru
Tipo de estudo:
Observational_studies
Limite:
Female
/
Humans
/
Male
/
Newborn
País/Região como assunto:
America do norte
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article