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The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation.
Dahl, Jan-Ulrik; Gray, Michael J; Bazopoulou, Daphne; Beaufay, Francois; Lempart, Justine; Koenigsknecht, Mark J; Wang, Ying; Baker, Jason R; Hasler, William L; Young, Vincent B; Sun, Duxin; Jakob, Ursula.
Afiliação
  • Dahl JU; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Gray MJ; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Bazopoulou D; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Beaufay F; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Lempart J; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Koenigsknecht MJ; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Wang Y; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Baker JR; Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Hasler WL; Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Young VB; Department of Internal Medicine/Division of Infectious Diseases &Department of Microbiology and Immunology, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.
  • Sun D; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Jakob U; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
Nat Microbiol ; 2: 16267, 2017 Jan 23.
Article em En | MEDLINE | ID: mdl-28112760

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polifosfatos / Anti-Inflamatórios não Esteroides / Mesalamina / Microbioma Gastrointestinal / Bactérias Gram-Negativas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polifosfatos / Anti-Inflamatórios não Esteroides / Mesalamina / Microbioma Gastrointestinal / Bactérias Gram-Negativas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article