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Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner.
Molina, Samuel A; Moriarty, Hannah K; Infield, Daniel T; Imhoff, Barry R; Vance, Rachel J; Kim, Agnes H; Hansen, Jason M; Hunt, William R; Koval, Michael; McCarty, Nael A.
Afiliação
  • Molina SA; Emory+Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia; s.a.molina@emory.edu.
  • Moriarty HK; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
  • Infield DT; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
  • Imhoff BR; Emory+Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
  • Vance RJ; Division of Pulmonology, Allergy & Immunology, Cystic Fibrosis and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; and.
  • Kim AH; Emory+Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
  • Hansen JM; Division of Pulmonology, Allergy & Immunology, Cystic Fibrosis and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; and.
  • Hunt WR; Emory+Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
  • Koval M; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
  • McCarty NA; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Am J Physiol Lung Cell Mol Physiol ; 312(5): L688-L702, 2017 05 01.
Article em En | MEDLINE | ID: mdl-28213469

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Regulador de Condutância Transmembrana em Fibrose Cística / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Insulina / Pulmão Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Regulador de Condutância Transmembrana em Fibrose Cística / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Insulina / Pulmão Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article