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Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase.
Neckles, Carla; Eltschkner, Sandra; Cummings, Jason E; Hirschbeck, Maria; Daryaee, Fereidoon; Bommineni, Gopal R; Zhang, Zhuo; Spagnuolo, Lauren; Yu, Weixuan; Davoodi, Shabnam; Slayden, Richard A; Kisker, Caroline; Tonge, Peter J.
Afiliação
  • Neckles C; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
  • Eltschkner S; Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg , D-97080 Würzburg, Germany.
  • Cummings JE; Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research and Department of Microbiology, Immunology and Pathology, Colorado State University , Fort Collins, Colorado 80523-0922, United States.
  • Hirschbeck M; Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg , D-97080 Würzburg, Germany.
  • Daryaee F; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
  • Bommineni GR; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
  • Zhang Z; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
  • Spagnuolo L; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
  • Yu W; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
  • Davoodi S; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
  • Slayden RA; Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research and Department of Microbiology, Immunology and Pathology, Colorado State University , Fort Collins, Colorado 80523-0922, United States.
  • Kisker C; Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg , D-97080 Würzburg, Germany.
  • Tonge PJ; Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University , Stony Brook, New York 11794, United States.
Biochemistry ; 56(13): 1865-1878, 2017 04 04.
Article em En | MEDLINE | ID: mdl-28225601

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Éteres Fenílicos / Proteínas de Bactérias / Burkholderia pseudomallei / Inibidores Enzimáticos / Enoil-(Proteína de Transporte de Acila) Redutase (NADH) / Melioidose / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Éteres Fenílicos / Proteínas de Bactérias / Burkholderia pseudomallei / Inibidores Enzimáticos / Enoil-(Proteína de Transporte de Acila) Redutase (NADH) / Melioidose / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article