[Relation between waist circumference and risk of male lung cancer incidence: a prospective cohort study].
Zhonghua Liu Xing Bing Xue Za Zhi
; 38(2): 137-141, 2017 Feb 10.
Article
em Zh
| MEDLINE
| ID: mdl-28231654
ABSTRACT
Objective:
To investigate the association between waist circumference and risk of male lung cancer incidence.Methods:
Since May 1, 2006, all the male employees including the retirees in Kailuan Group had been recruited into a Chinese Kailuan Male Cohort study. Information on anthropometries including body weight, height and waist circumference were collected at the baseline investigation, as well as information on newly-diagnosed lung cancer cases during the follow-up period. Waist circumference was grouped by quintiles of the population waist circumference distribution and categorized into the following five groups <80, 80-, 85-, 90- and ≥95 cm, with the relevant normal group, the second quintile group (80-cm), serving as the referent category. Multivariable Cox proportional hazards regression models were used to evaluate the association between levels of waist circumference and risk of lung cancer.Results:
A total of 105 386 males were recruited in the study, with 739 651.13 person-years of follow-up and an average follow-up period of 7.00 years. By the end of 2014, a total of 707 lung cancer cases were identified in the cohort study. Compared with males having the 80-cm of waist circumference, the hazard ratio (HR) and 95% confidence intervals (CI) of lung cancer were 1.17(0.90-1.52), 0.96(0.74-1.23), 0.94(0.72-1.21) and 0.80(0.63-1.03) for the <80, 85-, 90- and ≥95 cm of waist circumference, after adjustment for potential confounding factors including age, education level, smoking status and pack-year amount, alcohol consumption, physical activities, environment for working place and the prevalence on diabetes. The inverse association existed in smokers (≥95 cm compared to 80-cm of waist circumference HR=0.69, 95%CI 0.48-0.99) and alcohol drinkers (≥95 cm compared to 80-cm of waist circumference HR=0.65, 95%CI 0.45-0.94) when analysis was conducted in subgroups stratified by smoking or alcohol drinking status.Conclusion:
Waist circumference might be inversely associated with male lung cancer risk.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fumar
/
Circunferência da Cintura
/
Neoplasias Pulmonares
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Ano de publicação:
2017
Tipo de documento:
Article