Utility of Second-Generation Line Probe Assay (Hain MTBDR<i>plus</i>) Directly on 2-Month Sputum Specimens for Monitoring Tuberculosis Treatment Response.

Rockwood, Neesha; Wojno, Justyna; Ghebrekristos, Yonas; Nicol, Mark P; Meintjes, Graeme; Wilkinson, Robert J

Utility of Second-Generation Line Probe Assay (Hain MTBDRplus) Directly on 2-Month Sputum Specimens for Monitoring Tuberculosis Treatment Response.

Rockwood, Neesha; Wojno, Justyna; Ghebrekristos, Yonas; Nicol, Mark P; Meintjes, Graeme; Wilkinson, Robert J.

Afiliação

Rockwood N; Department of Medicine, Imperial College, London, United Kingdom neesha.rockwood@doctors.org.uk.
Wojno J; Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, Republic of South Africa.
Ghebrekristos Y; National Health Laboratory Service, Groote Schuur Hospital, Cape Town, Republic of South Africa.
Nicol MP; Division of Microbiology, Department of Pathology, University of Cape Town, Cape Town, Republic of South Africa.
Meintjes G; National Health Laboratory Service, Groote Schuur Hospital, Cape Town, Republic of South Africa.
Wilkinson RJ; Division of Microbiology, Department of Pathology, University of Cape Town, Cape Town, Republic of South Africa.

J Clin Microbiol ; 55(5): 1508-1515, 2017 05.

Article em En | MEDLINE | ID: mdl-28249999

Assuntos

Antituberculosos/uso terapêutico; Isoniazida/uso terapêutico; Rifampina/uso terapêutico; Escarro/microbiologia; Tuberculose Resistente a Múltiplos Medicamentos/tratamento farmacológico; Tuberculose Pulmonar/tratamento farmacológico; Farmacorresistência Bacteriana; Humanos; Testes de Sensibilidade Microbiana; Técnicas de Diagnóstico Molecular/métodos; Mycobacterium tuberculosis/efeitos dos fármacos; Estudos Prospectivos; Resultado do Tratamento; Tuberculose Resistente a Múltiplos Medicamentos/diagnóstico; Tuberculose Resistente a Múltiplos Medicamentos/microbiologia; Tuberculose Pulmonar/diagnóstico; Tuberculose Pulmonar/microbiologia

Palavras-chave

bacterial biomarker; drug resistance; line probe assay; treatment outcome; tuberculosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rifampina / Escarro / Tuberculose Pulmonar / Tuberculose Resistente a Múltiplos Medicamentos / Isoniazida / Antituberculosos Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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