Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MS<sup>n</sup> , and LC-HR-MS/MS.

Caspar, Achim T; Gaab, Jonas B; Michely, Julian A; Brandt, Simon D; Meyer, Markus R; Maurer, Hans H

Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSⁿ , and LC-HR-MS/MS.

Caspar, Achim T; Gaab, Jonas B; Michely, Julian A; Brandt, Simon D; Meyer, Markus R; Maurer, Hans H.

Afiliação

Caspar AT; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical, Pharmacology and Toxicology, Saarland University, Kirrberger Str. 100, Building 46, D-66421, Homburg (Saar), Germany.
Gaab JB; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical, Pharmacology and Toxicology, Saarland University, Kirrberger Str. 100, Building 46, D-66421, Homburg (Saar), Germany.
Michely JA; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical, Pharmacology and Toxicology, Saarland University, Kirrberger Str. 100, Building 46, D-66421, Homburg (Saar), Germany.
Brandt SD; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James, Parsons Building, Byrom Street, Liverpool, L3 3AF, UK.
Meyer MR; The Alexander Shulgin Research Institute, 1483 Shulgin Road, Lafayette, CA, 94549, USA.
Maurer HH; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical, Pharmacology and Toxicology, Saarland University, Kirrberger Str. 100, Building 46, D-66421, Homburg (Saar), Germany.

Drug Test Anal ; 10(1): 184-195, 2018 Jan.

Article em En | MEDLINE | ID: mdl-28342193

Assuntos

5-Metoxitriptamina/análogos & derivados; Compostos Alílicos/metabolismo; Óxidos N-Cíclicos/metabolismo; Cromatografia Gasosa-Espectrometria de Massas/métodos; Psicotrópicos/metabolismo; Espectrometria de Massas em Tandem/métodos; Triptaminas/metabolismo; 5-Metoxitriptamina/química; 5-Metoxitriptamina/metabolismo; 5-Metoxitriptamina/urina; Compostos Alílicos/química; Compostos Alílicos/urina; Cromatografia Líquida/métodos; Cromatografia Líquida/normas; Óxidos N-Cíclicos/química; Óxidos N-Cíclicos/urina; Cromatografia Gasosa-Espectrometria de Massas/normas; Humanos; Psicotrópicos/química; Psicotrópicos/urina; Detecção do Abuso de Substâncias/métodos; Detecção do Abuso de Substâncias/normas; Espectrometria de Massas em Tandem/normas; Triptaminas/química; Triptaminas/urina

Palavras-chave

LC-HR-MS/MS; LC-MSn; cytochrome-P450; metabolism; new psychoactive substances; tryptamines

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psicotrópicos / Triptaminas / 5-Metoxitriptamina / Óxidos N-Cíclicos / Compostos Alílicos / Espectrometria de Massas em Tandem / Cromatografia Gasosa-Espectrometria de Massas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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