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The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase.
Estoppey, David; Lee, Chia Min; Janoschke, Marco; Lee, Boon Heng; Wan, Kah Fei; Dong, Hongping; Mathys, Philippe; Filipuzzi, Ireos; Schuhmann, Tim; Riedl, Ralph; Aust, Thomas; Galuba, Olaf; McAllister, Gregory; Russ, Carsten; Spiess, Martin; Bouwmeester, Tewis; Bonamy, Ghislain M C; Hoepfner, Dominic.
Afiliação
  • Estoppey D; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • Lee CM; Novartis Institute for Tropical Diseases, 10 Biopolis Road, Chromos #05-01, 138670 Singapore, Singapore.
  • Janoschke M; Biozentrum, University of Basel, Klingelbergstrasse 50/70, 4056 Basel, Switzerland.
  • Lee BH; Novartis Institute for Tropical Diseases, 10 Biopolis Road, Chromos #05-01, 138670 Singapore, Singapore.
  • Wan KF; Novartis Institute for Tropical Diseases, 10 Biopolis Road, Chromos #05-01, 138670 Singapore, Singapore.
  • Dong H; Novartis Institute for Tropical Diseases, 10 Biopolis Road, Chromos #05-01, 138670 Singapore, Singapore.
  • Mathys P; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • Filipuzzi I; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • Schuhmann T; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • Riedl R; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • Aust T; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • Galuba O; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • McAllister G; Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Russ C; Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • Spiess M; Biozentrum, University of Basel, Klingelbergstrasse 50/70, 4056 Basel, Switzerland.
  • Bouwmeester T; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland.
  • Bonamy GMC; Novartis Institute for Tropical Diseases, 10 Biopolis Road, Chromos #05-01, 138670 Singapore, Singapore. Electronic address: bonamgh1@gmail.com.
  • Hoepfner D; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, 4056 Basel, Switzerland; Biozentrum, University of Basel, Klingelbergstrasse 50/70, 4056 Basel, Switzerland. Electronic address: dominic.hoepfner@novartis.com.
Cell Rep ; 19(3): 451-460, 2017 04 18.
Article em En | MEDLINE | ID: mdl-28423309
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação Viral / Produtos Biológicos / Vírus da Dengue / Lipopeptídeos / Zika virus Tipo de estudo: Guideline Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação Viral / Produtos Biológicos / Vírus da Dengue / Lipopeptídeos / Zika virus Tipo de estudo: Guideline Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article