Designing structural features of novel benznidazole-loaded cationic nanoparticles for inducing slow drug release and improvement of biological efficacy.

Dos Santos-Silva, Alaine M; de Caland, Lilia B; de S L Oliveira, Ana Luíza C; de Araújo-Júnior, Raimundo F; Fernandes-Pedrosa, Matheus F; Cornélio, Alianda Maira; da Silva-Júnior, Arnóbio A

Dos Santos-Silva, Alaine M; de Caland, Lilia B; de S L Oliveira, Ana Luíza C; de Araújo-Júnior, Raimundo F; Fernandes-Pedrosa, Matheus F; Cornélio, Alianda Maira; da Silva-Júnior, Arnóbio A.

Afiliação

Dos Santos-Silva AM; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
de Caland LB; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
de S L Oliveira ALC; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
de Araújo-Júnior RF; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Fernandes-Pedrosa MF; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Cornélio AM; Department of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal, - RN, Brazil.
da Silva-Júnior AA; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil. Electronic address: arnobiosilva@gmail.com.

Mater Sci Eng C Mater Biol Appl ; 78: 978-987, 2017 Sep 01.

Article em En | MEDLINE | ID: mdl-28576075

Assuntos

Nanopartículas; Portadores de Fármacos; Liberação Controlada de Fármacos; Células HEK293; Humanos; Nitroimidazóis; Tamanho da Partícula

Palavras-chave

Benznidazol; Biomedical materials; Cancer; Cationic nanoparticles; Drug targeting; Nanostructures characterization

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article