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Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins.
Littler, Dene R; Ang, Sheng Y; Moriel, Danilo G; Kocan, Martina; Kleifeld, Oded; Johnson, Matthew D; Tran, Mai T; Paton, Adrienne W; Paton, James C; Summers, Roger J; Schembri, Mark A; Rossjohn, Jamie; Beddoe, Travis.
Afiliação
  • Littler DR; From the Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Ang SY; the Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Moriel DG; the School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.
  • Kocan M; the Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Kleifeld O; the Faculty of Biology, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
  • Johnson MD; From the Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Tran MT; From the Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Paton AW; the Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, South Australia 5005, Australia.
  • Paton JC; the Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, South Australia 5005, Australia.
  • Summers RJ; the Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Schembri MA; the School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.
  • Rossjohn J; From the Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia, jamie.rossjohn@monash.edu.au.
  • Beddoe T; the Institute of Infection and Immunity, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, Wales, United Kingdom.
J Biol Chem ; 292(36): 15143-15158, 2017 09 08.
Article em En | MEDLINE | ID: mdl-28663369
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxinas Bacterianas / Proteínas Heterotriméricas de Ligação ao GTP / Toxina Pertussis / Escherichia coli Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxinas Bacterianas / Proteínas Heterotriméricas de Ligação ao GTP / Toxina Pertussis / Escherichia coli Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article