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QSAR modeling and in silico design of small-molecule inhibitors targeting the interaction between E3 ligase VHL and HIF-1α.
Pan, Jing; Zhang, Yanmin; Ran, Ting; Xu, Anyang; Qiao, Xin; Yin, Lingfeng; Zhou, Weineng; Zhu, Lu; Zhao, Junnan; Lu, Tao; Chen, Yadong; Jiang, Yulei.
Afiliação
  • Pan J; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Zhang Y; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Ran T; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Xu A; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Qiao X; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Yin L; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Zhou W; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Zhu L; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Zhao J; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Lu T; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.
  • Chen Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, China.
  • Jiang Y; Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China. ydchen@cpu.edu.cn.
Mol Divers ; 21(3): 719-739, 2017 08.
Article em En | MEDLINE | ID: mdl-28689235
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor Von Hippel-Lindau / Subunidade alfa do Fator 1 Induzível por Hipóxia / Bibliotecas de Moléculas Pequenas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor Von Hippel-Lindau / Subunidade alfa do Fator 1 Induzível por Hipóxia / Bibliotecas de Moléculas Pequenas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article