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Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.
Zhang, Bang-Hong; Lei, Lin-Sheng; Liu, Si-Zhan; Mou, Xue-Qing; Liu, Wei-Ting; Wang, Shao-Hua; Wang, Jie; Bao, Wen; Zhang, Kun.
Afiliação
  • Zhang BH; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn.
  • Lei LS; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn.
  • Liu SZ; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn.
  • Mou XQ; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn.
  • Liu WT; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn.
  • Wang SH; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn and School of Chemical and Environmental Engineering, Wuyi University, Jiangmen 529020, P. R. China and Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, Sichuan University, Chengd
  • Wang J; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn.
  • Bao W; School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China. wangshh@lzu.edu.cn.
  • Zhang K; School of Chemical and Environmental Engineering, Wuyi University, Jiangmen 529020, P. R. China.
Chem Commun (Camb) ; 53(61): 8545-8548, 2017 Jul 27.
Article em En | MEDLINE | ID: mdl-28707696
ABSTRACT
A Zn(OTf)2-promoted cyclization reaction of tosylhydrazones with 2-(dimethylamino)malononitrile has been successfully developed providing an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article