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Do TRPV1 antagonists increase the risk for skin tumourigenesis? A collaborative in vitro and in vivo assessment.
Park, Miyoung; Naidoo, Anita A; Burns, Angie; Choi, Jin Kyu; Gatfield, Kelly M; Vidgeon-Hart, Martin; Bae, Il-Hong; Lee, Chang Seok; Choi, Gyeyoung; Powell, Andrew J; Park, Young-Ho; Fagg, Rajni.
Afiliação
  • Park M; Vital Beautie Research Institute, AmorePacific Corporation R&D Centre, Yongin, South Korea. mypark@amorepacific.com.
  • Naidoo AA; Department of Investigative Safety and Drug Metabolism, GlaxoSmithKline Research and Development, Ware, Hertfordshire, SG12 0DP, UK. anita.a.naidoo@gsk.com.
  • Burns A; Department of Toxicology and Drug Metabolism, GlaxoSmithKline Research and Development, Ware, Hertfordshire, SG12 0DP, UK.
  • Choi JK; Medical Beauty QA Team, Aestura, Anseong, South Korea.
  • Gatfield KM; Department of Screening, Profiling and Mechanistic Biology, GlaxoSmithKline Research and Development, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Vidgeon-Hart M; Department of Investigative Safety and Drug Metabolism, GlaxoSmithKline Research and Development, Ware, Hertfordshire, SG12 0DP, UK.
  • Bae IH; Vital Beautie Research Institute, AmorePacific Corporation R&D Centre, Yongin, South Korea.
  • Lee CS; Vital Beautie Research Institute, AmorePacific Corporation R&D Centre, Yongin, South Korea.
  • Choi G; Vital Beautie Research Institute, AmorePacific Corporation R&D Centre, Yongin, South Korea.
  • Powell AJ; Department of Screening, Profiling and Mechanistic Biology, GlaxoSmithKline Research and Development, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Park YH; Vital Beautie Research Institute, AmorePacific Corporation R&D Centre, Yongin, South Korea.
  • Fagg R; Department of Translation Platform Project Specialists, GlaxoSmithKline Research and Development, Ware, Hertfordshire, SG12 0DP, UK.
Cell Biol Toxicol ; 34(2): 143-162, 2018 04.
Article em En | MEDLINE | ID: mdl-28815372
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Queratinócitos / Proliferação de Células / Canais de Cátion TRPV Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Queratinócitos / Proliferação de Células / Canais de Cátion TRPV Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article