Your browser doesn't support javascript.
loading
[Lymphocytic myocarditis in a patient with metastatic clear cell renal cell carcinoma treated with Nivolumab]. / Lymphozytäre Myokarditis unter Nivolumabtherapie bei metastasiertem klarzelligen Nierenzellkarzinom.
Sauer, R; Kiewe, P; Desole, M; Schuler, M; Theissig, F; Roth, A; Mairinger, T.
Afiliação
  • Sauer R; Institut für Pathologie, MVZ am HELIOS Klinikum Emil von Behring, Walterhöferstr. 11, 14165, Berlin, Deutschland. rica.sauer@helios-kliniken.de.
  • Kiewe P; MVZ Onkologischer Schwerpunkt am Oskar-Helene-Heim, Berlin, Deutschland.
  • Desole M; Klinik für Innere Medizin II, HELIOS Klinikum Emil von Behring, Berlin, Deutschland.
  • Schuler M; Klinik für Innere Medizin II, HELIOS Klinikum Emil von Behring, Berlin, Deutschland.
  • Theissig F; Institut für Pathologie, MVZ am HELIOS Klinikum Emil von Behring, Walterhöferstr. 11, 14165, Berlin, Deutschland.
  • Roth A; Institut für Pathologie, MVZ am HELIOS Klinikum Emil von Behring, Walterhöferstr. 11, 14165, Berlin, Deutschland.
  • Mairinger T; Institut für Pathologie, MVZ am HELIOS Klinikum Emil von Behring, Walterhöferstr. 11, 14165, Berlin, Deutschland.
Pathologe ; 38(6): 535-539, 2017 Nov.
Article em De | MEDLINE | ID: mdl-28819833
Immune checkpoint inhibitors against the PD-1 protein offer a new therapy option for many solid cancers. We report a patient with metastatic renal cell cancer treated with Nivolumab. As a rare immune-mediated adverse event, we describe a fatal lymphocytic myocarditis two weeks after starting immune therapy. The cause of death was first diagnosed at autopsy. This case report underlines the importance and need of clinical autopsies as an instrument of quality assurance and detection of rare therapy-induced adverse effects.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Nivolumabe / Neoplasias Renais / Miocardite Limite: Humans Idioma: De Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Nivolumabe / Neoplasias Renais / Miocardite Limite: Humans Idioma: De Ano de publicação: 2017 Tipo de documento: Article