[Lymphocytic myocarditis in a patient with metastatic clear cell renal cell carcinoma treated with Nivolumab]. / Lymphozytäre Myokarditis unter Nivolumabtherapie bei metastasiertem klarzelligen Nierenzellkarzinom.
Pathologe
; 38(6): 535-539, 2017 Nov.
Article
em De
| MEDLINE
| ID: mdl-28819833
Immune checkpoint inhibitors against the PD-1 protein offer a new therapy option for many solid cancers. We report a patient with metastatic renal cell cancer treated with Nivolumab. As a rare immune-mediated adverse event, we describe a fatal lymphocytic myocarditis two weeks after starting immune therapy. The cause of death was first diagnosed at autopsy. This case report underlines the importance and need of clinical autopsies as an instrument of quality assurance and detection of rare therapy-induced adverse effects.
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MEDLINE
Assunto principal:
Carcinoma de Células Renais
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Nivolumabe
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Neoplasias Renais
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Miocardite
Limite:
Humans
Idioma:
De
Ano de publicação:
2017
Tipo de documento:
Article