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Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis.
Tripathi, Siddharth K; Xu, Tao; Feng, Qin; Avula, Bharathi; Shi, Xiaomin; Pan, Xuewen; Mask, Melanie M; Baerson, Scott R; Jacob, Melissa R; Ravu, Ranga Rao; Khan, Shabana I; Li, Xing-Cong; Khan, Ikhlas A; Clark, Alice M; Agarwal, Ameeta K.
Afiliação
  • Tripathi SK; From the National Center for Natural Products Research.
  • Xu T; From the National Center for Natural Products Research.
  • Feng Q; From the National Center for Natural Products Research.
  • Avula B; From the National Center for Natural Products Research.
  • Shi X; the Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, and.
  • Pan X; the Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, and.
  • Mask MM; the United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University, Mississippi 38677.
  • Baerson SR; the United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University, Mississippi 38677.
  • Jacob MR; From the National Center for Natural Products Research.
  • Ravu RR; From the National Center for Natural Products Research.
  • Khan SI; From the National Center for Natural Products Research.
  • Li XC; the Divisions of Pharmacognosy and.
  • Khan IA; From the National Center for Natural Products Research.
  • Clark AM; the Divisions of Pharmacognosy and.
  • Agarwal AK; From the National Center for Natural Products Research.
J Biol Chem ; 292(40): 16578-16593, 2017 10 06.
Article em En | MEDLINE | ID: mdl-28821607
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aporfinas / Candida albicans / Proteínas Fúngicas / Proteínas Mitocondriais / Indenos / Proteínas Ferro-Enxofre / Antifúngicos / Naftiridinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aporfinas / Candida albicans / Proteínas Fúngicas / Proteínas Mitocondriais / Indenos / Proteínas Ferro-Enxofre / Antifúngicos / Naftiridinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article