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Change in the structure and function of lectin by photodissociation of NO.
Kurota, T; Sato, I; Kuroi, K; Hiramatsu, H; Nakabayashi, T.
Afiliação
  • Kurota T; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan. takan@m.tohoku.ac.jp.
  • Sato I; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan. takan@m.tohoku.ac.jp.
  • Kuroi K; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan. takan@m.tohoku.ac.jp.
  • Hiramatsu H; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan. takan@m.tohoku.ac.jp and Department of Applied Chemistry and Institute of Molecular Science, National Chiao Tung University, 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan. hiramatu@nctu.edu.tw.
  • Nakabayashi T; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan. takan@m.tohoku.ac.jp.
Chem Commun (Camb) ; 53(72): 10014-10017, 2017 Sep 16.
Article em En | MEDLINE | ID: mdl-28835961
ABSTRACT
We have shown here that the structure and sugar-binding activity of lectin can be changed by the photodissociation of NO. Intramolecular S-S bonds are photogenerated from SNO in the protein, which can be used to photo-control the structure and function of proteins.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article